Bacterial growth inhibition by amniotic fluid

Autor: Larsen, Bryan, Snyder, Irvin S., Galask, Rudolph P.
Zdroj: American Journal of Obstetrics and Gynecology; June 1974, Vol. 119 Issue: 4 p492-496, 5p
Abstrakt: By measuring bacterial growth spectrophotometrically, it has been demonstrated that amniotic fluid fails to support the growth of Escherichia coli, Streptococcus faecalis, and Staphylococcus aureus. Dilution of amniotic fluid in water prior to addition of an inoculum of Escherichia coliresults in a loss of inhibition. Comparable results are obtained whether growth is monitored by plate count or spectrophotometry. Plate-count studies revealed that amniotic fluid may be diluted to 30 per cent of its original concentration and still retain enough inhibitory activity to maintain bacterial counts at a lower level than for an equivalent inoculum in distilled water. Growth of Escherichia coliin amniotic fluid is inversely related to amniotic fluid concentration. Amniotic fluid does not fail to support bacterial growth because of nutritional inadequacy but contains some material which suppresses bacterial growth.
Databáze: Supplemental Index