| Autor: |
Lurie, Aron O., Weiss, Jess B. |
| Zdroj: |
American Journal of Obstetrics and Gynecology; March 1970, Vol. 106 Issue: 6 p850-856, 7p |
| Abstrakt: |
The concentration of mepivacaine and lidocaine in mother and neonate was assayed by means of gas liquid chromatography. There was a rapid appearance of the drug in the maternal circulation, mean peak concentration being attained within 5 minutes. In 19 cases of mepivacaine anesthesia the mean maternal blood concentration was 2.2 μg per milliliter, whereas in the neonate the mean concentration was 1.6 μg per milliliter. In 13 cases of lidocaine anesthesia the mean maternal blood concentration was 2.2 μg per milliliter and in the neonate 1.55 μg per milliliter. Three neonates required resuscitation and in these cases the duration of anesthesia was greater than 6 hours with a total dosage of anesthetic agent greater than 600 mg. The mothers showed no side effects attributable to the anesthetic agents. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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