| Autor: |
James, L.S., Morishima, H.O., Daniel, S.S., Bowe, E.T., Cohen, H., Niemann, W.H. |
| Zdroj: |
American Journal of Obstetrics and Gynecology; July 1972, Vol. 113 Issue: 5 p578-582, 5p |
| Abstrakt: |
An experimental model in the subhuman primate where the cardiovascular and acid-base state of the near-term fetus can be directly monitored during labor has been developed in our laboratory. The relationship between late deceleration of the fetal heart rate, acid-base state, and level of oxygenation was studied in a series of 30 experiments. In those fetuses which became acidotic, hypoxic, and hypotensive as labor advanced, there was an increase in base-line heart rate and late deceleration of the fetal heart rate following each uterine contraction. The late deceleration appeared as a marked transient bradycardia and was accompanied by a further decrease in fetal oxygen levels. In those fetuses which remained well oxygenated, there was no change in heart rate or in the level of oxygenation during uterine contractions of similar intensity. Late deceleration was abolished or suppressed when the level of fetal oxygenation was increased by administering a high concentration of oxygen to the mother. Since the fetal acidosis and hypotension remained, it is concluded that fetal hypoxia is the essential component producing late deceleration of the heart rate. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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