Rubella vaccine program: Its implications in obstetric practice

Autor: Maeck, John Van S., Phillips, Charles A.
Zdroj: American Journal of Obstetrics and Gynecology; February 1972, Vol. 112 Issue: 4 p513-518, 6p
Abstrakt: Questions concerning the ability of the rubella vaccine program to protect women from first trimester rubella infection underscore the need for serologic screening of all women in childbearing age for the presence of rubella antibody. Priority should be given to high-risk groups and consideration should be given to including this test in the premarital and pregnancy laboratory studies. Staff nurses of childbearing age and student nurses at the Medical Center Hospital of Vermont were screened for the presence of rubella HI antibody. Of the staff nurses, 12 of 144 (8.3 per cent) had no antibody. Of 229 student nurses, 17 (7.4 per cent) had no antibody. Seventeen seronegative nurses were given HPV77W16 rubella vaccine and all seroconverted. Four noted transient arthritis and arthralgias of the hands and knees. Serologic screening of a private obstetric practice and of an entire high school proved feasible and revealed that 22 of 214 (10.3 per cent) pregnant women and 56 of 261 (21.5 per cent) high school girls lacked antibody. Immunization was recommended for nonpregnant seronegative women and for pregnant women only at the termination of pregnancy.
Databáze: Supplemental Index