Massive colonic bleeding and oral contraceptive “pills”

Autor: Prust, Frank W., Kumar, G.Krishna
Zdroj: American Journal of Obstetrics and Gynecology; July 1976, Vol. 125 Issue: 5 p695-698, 4p
Abstrakt: Two patients on oral contraceptives who developed massive colonic bleeding have been presented. The clinical course and various studies suggest the mesenteric insufficiency syndrome as being a possible result of oral contraceptive effect on mesenteric vasculature. Although no definite histologic confirmation is available, the onset, course, and follow-up of these patients suggest contraceptive-induced massive colonic bleeding. The spectrum of oral contraceptive-induced colonic bleeding may vary from mucosal injury with massive colonic bleeding to transmural infarction. Only the clinical follow-up would determine the severity of the involvement and that would determine whether surgical intervention will be necessary.
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