| Abstrakt: |
An analysis of 660 hydatidiform moles observed at the Concepcion Palacios Maternity Hospital, from Caracas, Venezuela, between 1939 and 1968, is presented. In 728,431 pregnancies in women of low socioeconomic level the frequency of hydatidiform mole was 1 per 1,088; in relation to 590,158 live births this frequency is of 1 per 894. In Venezuela there are wide variations of frequency, from 1 per 423 to 1 per 1,617 pregnancies. There was a higher incidence of hydatidiform mole in primigravidas. Ninety-four per cent of the pregnancies were terminated between 4 and 28 weeks of gestation; hemorrhage was the most frequent (96.5 per cent) clinical symptoms; and 77 per cent of the pregnancies were terminated in 48 hours after admission to the hospital. In 94 per cent a vaginal method of termination was employed. To our knowledge there was only 0.9 per cent of histologic malignant degeneration in 126 women who returned to the hospital. The main conclusion is that the reasons for a wide geographic variation in incidence of hydatidiform moles are still unknown. |
