| Autor: |
Woodbury, Robert A., Abreu, Benedict E. |
| Zdroj: |
American Journal of Obstetrics and Gynecology; November 1944, Vol. 48 Issue: 5 p706-708, 3p |
| Abstrakt: |
Rucker1in 1925, called attention to the fact that studies published concerning the action of epinephrine showed opposite effects in different animals and even in the same species of animals with various conditions of the uterus. In his studies on intrauterine pressures of 20 pregnant human beings, he observed that epinephrine decreased uterine activity in 80 per cent of the patients. The results of Bourne2and of those from this laboratory3indicate that in human beings, epinephrine causes an initial brief period of increased activity followed by a short period of reduced uterine activity. Recently, Brown and Wilder4–6quote these latter studies to disprove Rucker's statement that epinephrine relaxes the uterus. It is a common pharmacologic observation that epinephrine in proper dosage can produce either excitatory and/or inhibitory effects upon a number of structures innervated by the sympathetic nervous system. Both actions may be present and may tend to counterbalance each other. The present studies were undertaken to determine whether epinephrine has both stimulatory and inhibitory actions upon the human pregnant uterus. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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