Organic synthesis in solid media. Solvent-free Horner–Wadsworth–Emmons reaction in silica gel

Autor: Jin, Yong Zhi, Yasuda, Noriyuki, Inanaga, Junji
Zdroj: Green Chemistry; October 4, 2002, Vol. 4 Issue: 5 p498-500, 3p
Abstrakt: Silica gel was found to be an excellent medium for the aldehyde-selective Horner-Wadsworth-Emmons reaction, which proceeds at room temperature in a short period of time under solvent-free conditions. The silica gel used for the reaction can be recovered and reused many times without losing its activity.
Databáze: Supplemental Index