| Autor: |
Campbell, Gordon R., Ryan, G.B. |
| Zdroj: |
Pathology; January 1983, Vol. 15 Issue: 3 p253-264, 12p |
| Abstrakt: |
The origin of cells comprising the capsule which forms around free-floating intraperitoneal blood clots has been examined in rats One day after implantation the surface of the clot was covered by 1-2 layers of rounded nucleated cells The majority of these cells were monocyte/macrophage in type with many cytoplasmic folds Over the next 2wk a thick capsule composed of dense connective tissue and myofibroblasts developed, completely covering the clot The surface became covered by a contiguous layer of mesothelial cells apparently derived from displaced cells of the damaged peritoneum Detailed examination of the formation of the capsule suggested that a proportion of cells with the characterstic features of peritoneal macrophages gradually develop over a 3–4 d period the characteristic features of fibroblasts These cells with time then develop filament bundles and a basal lamina to become myofibroblasts |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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