Comparative effects of insulin and refeeding on DNA synthesis, HMP shunt and cholesterogenesis in diabetic and fasted rats

Autor: Dessi, Sandra, Chiodino, Caterina, Batetta, Barbara, Armeni, Marina, Mulas, Maria Franca, Pani, Paolo
Zdroj: Pathology; January 1988, Vol. 20 Issue: 1 p53-57, 5p
Abstrakt: DNA synthesis, cholesterogenesis and the enzymes of the hexosemonophosphate (HMP) shunt pathway were investigated in liver of diabetic rats treated with insulin and in fasted/re-fed rats. Both insulin and refeeding were found to induce liver cell proliferation, accompanied by a remarkable increase in cholesterogenesis.
Databáze: Supplemental Index