Common ALKgene rearrangement in Asian CD30+anaplastic large cell lymphoma: an immunohistochemical and fluorescence in situhybridisation (FISH) study on paraffin-embedded tissue

Autor: Tai, Yan Chin, Kim, Lian Hua, Peh, Suat Cheng
Zdroj: Pathology; October 2003, Vol. 35 Issue: 5 p436-443, 8p
Abstrakt: The most common recurrent genetic aberration in anaplastic large cell lymphoma (ALCL) is translocation involving the ALKgene that results in ectopic expression of ALK protein in lymphoid tissue. This study aims to investigate the frequency of ALKgene rearrangement in a series of Asian ALCL.
Databáze: Supplemental Index