No difference in the occurrence of mismatch repair defects and APCand CTNNB1genes mutation in a multi-racial colorectal carcinoma patient cohort

Autor: Ping Tan, Lu, Kim Ng, Ban, Balraj, Pauline, Kim Chooi Lim, Patricia, Cheng Peh, Suat
Zdroj: Pathology; April 2007, Vol. 39 Issue: 2 p228-234, 7p
Abstrakt: Colorectal cancers of different subtypes involve different pathogenic pathways like the Wnt and the mutator pathways. In this study, we screened 73 colorectal cancer cases from a multi-racial group for genetic and expression profile defects with the aim of correlating these with patients’ clinicopathological characteristics.
Databáze: Supplemental Index