Evidence for intrinsic proteolytic activity in rat liver plasma membranes

Autor: Guenet, Lucienne, Leray, Geneviève, Codet, Jean-Pierre, Le Treut, André, Le Gall, Jean-Yves
Zdroj: Biochemical and Biophysical Research Communications; September 1982, Vol. 108 Issue: 2 p486-494, 9p
Abstrakt: Electrophoresis on 10 % acrylamide-SDS gels showed that incubation of rat liver plasma membranes with certain detergents induces a proteolysis. The results obtained using different detergents, temperatures and pH levels, as well as the action of some protease inhibitors are in favor of an enzymatically-induced proteolysis. Since the proteolytic activity remains unchanged, even after the peripheral proteins have been released, it is proposed that this activity may reflect one of the integral proteins functions.
Databáze: Supplemental Index