Diagnostic Value of Carcinoembryonic Antigen in Exudative Pleural Effusions

Autor: McKenna, James M., Chandrasekhar, Arcot J., Henkin, Robert E.
Zdroj: Chest; October 1980, Vol. 78 Issue: 4 p587-590, 4p
Abstrakt: Elevated pleural fluid (PF) and plasma (PL) carcinoembryonic antigen (CEA) levels (ng/ml) were more frequently found with malignant than benign exudative effusions, but with a low true-positive rate for malignancy in general. Adenocarcinomatous effusions differed from other malignant and benign effusions in the frequency and degree of elevation of PF and PL CEA levels. A PF > 20 had a sensitivity of 91 percent and a specificity of 92 percent as a screening test for adenocarcinomatous effusions. A PF CEA >55 or PL CEA >10 were present only with malignancy and 98 percent specific for adenocarcinoma.
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