Carcinoma ex-pleomorphic adenoma derived from recurrent pleomorphic adenoma shows important difference by array CGH compared to recurrent pleomorphic adenoma without malignant transformation

Autor: Mariano, Fernanda Viviane, Giovanetti, Karina, Saccomani, Luis Fernando Vidal, Del Negro, André, Kowalski, Luiz Paulo, Krepischi, Ana Cristina Victorino, Altemani, Albina
Zdroj: Brazilian Journal of Otorhinolaryngology; 20240101, Issue: Preprints
Abstrakt: A key step of cancer development is the progressive accumulation of genomic changes resulting in disruption of several biological mechanisms. Carcinoma ex-pleomorphic adenoma (CXPA) is an aggressive neoplasm that arises from a pleomorphic adenoma. CXPA derived from a recurrent PA (RPA) has been rarely reported, and the genomic changes associated with these tumors have not yet been studied.
Databáze: Supplemental Index