Immunization with antigenic extracts of Leishmaniaassociated with Montanide ISA 763 adjuvant induces partial protection in BALB/c mice against Leishmania (Leishmania) amazonensisinfection

Autor: Cargnelutti, Diego Esteban, Salomón, María Cristina, Celedon, Verónica, García Bustos, María Fernanda, Morea, Gastón, Cuello-Carrión, Fernando Darío, Scodeller, Eduardo Alberto
Zdroj: Journal of Microbiology, Immunology and Infection; February 2016, Vol. 49 Issue: 1 p24-32, 9p
Abstrakt: A proper adjuvant has a relevant role in vaccine formulations to generate an effective immune response. In this study, total Leishmaniaantigen (TLA) formulated with Montanide ISA 763 or R848 as adjuvants were evaluated as a first generation Leishmaniavaccine in a murine model.
Databáze: Supplemental Index