| Autor: |
Raina, Jyotdeep K., Sharma, Minakashee, Panjaliya, Rakesh K., Bhagat, Minakshi, Sharma, Ravi, Bakaya, Ashok, Kumar, Parvinder |
| Zdroj: |
Indian Heart Journal; May-June 2016, Vol. 68 Issue: 3 p421-430, 10p |
| Abstrakt: |
Potent risk factors at both genetic and non-genetic levels are accountable for susceptibility and instigation of different cardiovascular phenotypes. Recently, homocysteine is being identified as an important predictor for cardiovascular diseases. Homocysteine remethylation plays a key role in the synthesis of methionine and S-adenosine methionine. Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR) genes are known to regulate the homocysteine remethylation reaction and higher homocysteine level is significantly associated with diverse cardiovascular phenotypes. In this context, we aimed to carry out a study on the association of MTHFR (C677T) and MTR (A2756G) gene polymorphism with CVD in population of Jammu region of J&K state. |
| Databáze: |
Supplemental Index |
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