Synthesis of Pyrazine Derivatives as Potential Hypoglycemic Agents

Autor: Ambrogi, V., Bloch, K., Daturi, S., Logemann, W., Parenti, M.A.
Zdroj: Journal of Pharmaceutical Sciences; October 1972, Vol. 61 Issue: 9 p1483-1486, 4p
Abstrakt: A series of new pyrazine derivatives was synthesized and screened for hypoglycemic activity. Some of these compounds showed weak activity at high dosage levels. Pyrazinoyl-4-ethyl-thiosemicarbazide was active both in mice and rats.
Databáze: Supplemental Index