| Abstrakt: |
The aerial parts of Euphorbia esulawere subjected to a fractionation scheme which resulted, after several chromatographic separations, in the isolation of β-sitosterol, 24-methylenecycloartanol, hexacosanol-(1), n-nonacosane, and n-hentriacontane. The presence of n-pentacosane, n-hexacosane, n-heptacosane, n-octacosane, n-triacontane, n-dotriacontane, and n-tritriacontane was demonstrated by means of gas chromatography. None of these compounds had previously been reported as isolated from Euphorbia esula. The presence of flavonoids and alkaloids was demonstrated, a finding that is contrary to literature reports. A defatted ethanol extract elicited no antimicrobial activity against several test organisms and was found to induce only weak central nervous system depression in mice. Seven tumor systems were not inhibited by the extract, and it was not cytotoxic in cell culture. |
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