Synthesis of Compounds Containing the Isoindoline Ring System

Autor: Shoeb, Aboo, Gearien, James E.
Zdroj: Journal of Pharmaceutical Sciences; May 1962, Vol. 51 Issue: 5 p469-473, 5p
Abstrakt: In an attempt to gain further knowledge concerning the pharmacological properties inherent in the isoindoline ring system, a number of compounds containing this ring system were synthesized and screened for biological activity. These compounds are analogs of biologically active compounds. Only the amide of N-[3-(2-isoindolinyl)propyl]-beta-alanine demonstrated appreciable biological activity The carbon-hydrogen absorption bands present in the infrared spectra of these compounds were related to their chemical structure.
Databáze: Supplemental Index