| Abstrakt: |
Investigation of Dryopteris marginalishas resulted in the isolation of a new phloroglucinol derivative, m.p. 178–180°, designated margaspidin. Characterization studies have indicated that it is a two-ring compound consisting of butyryl-3-methylphloroglucinol (II) and aspidinol (V) linked by a methylene bridge (I). The structure (I) has been confirmed by synthesis. Six other phloroglucinol derivatives have been identified and four of them isolated in pure form. These compounds are albaspidin, desaspidin, flavaspidic acid, para-aspidin, phloraspin, and phloraspidinol, of which the first three have been chromatographically detected by previous workers. Margaspidin has been found to be the major compound in D. marginalisextracts, the content being about ten times higher than that of the other phloroglucinol derivatives present in this Dryopterisspecies. |
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