Syntheses and Hypotensive Properties of Substituted 2-Aminotetralins

Autor: Repke, David B., Clark, Robin D., Kluge, Arthur F., Muchowski, Joseph M., Strosberg, Arthur M., Lee, Chi-Ho, Whiting, Roger L.
Zdroj: Journal of Pharmaceutical Sciences; January 1985, Vol. 74 Issue: 1 p37-39, 3p
Abstrakt: The synthesis and activity in the spontaneously hypertensive rat of several 4-(1,2,3,4-tetrahydronaphthyl-2-amino)-1-(4-fluorophenyl)-1-butanones is reported. Maximal antihypertensive activity was associated with 5,6-dimethoxy substitution in the aminotetralin moiety.
Databáze: Supplemental Index