Biological and Phytochemical Evaluation of Plants XI: Isolation of Aspidospermine, Quebrachidine, Rhazinilam, (—)-Pyrifolidine, and Akuammidine from Aspidosperma Quebracho-blanco(Apocynaceae)

Autor: Lyon, R.L., Fong, H.H.S., Farnsworth, N.R., Svoboda, G.H.
Zdroj: Journal of Pharmaceutical Sciences; February 1973, Vol. 62 Issue: 2 p218-221, 4p
Abstrakt: A phytochemical investigation of the leaves of Aspidosperma quebracho-blanco(Apocynaceae) resulted in the isolation of rhazinilam, a new nonindole lactam alkaloid, in addition to the known bases, aspidospermine, quebrachidine, (—)-pyrifolidine, and akuammidine. Aspidospermine and quebrachidine were the major leaf alkaloids. Akuammidine and (—)-pyrifolidine were isolated from the leaves for the first time, and the isolation of the latter compound confirms its natural occurrence in this plant.
Databáze: Supplemental Index