Investigation of the Mechanism of Urea-Induced Hemolysis

Autor: Wurster, Dale E., Shapiro, Paul H.
Zdroj: Journal of Pharmaceutical Sciences; January 1963, Vol. 52 Issue: 1 p33-38, 6p
Abstrakt: The hemolysis of mammalian erythrocytes in concentrated urea solutions and in isotonic sodium chloride and dextrose solutions containing thirty per cent urea was investigated. Increased concentrations of sodium chloride, dextrose, and other osmotic agents inhibited the urea-induced hemolysis. The existence of urea-dextrose complexes in water, methanol, and methanol-water systems containing high dextrose concentrations were demonstrated.
Databáze: Supplemental Index