| Autor: |
Hundt, H.K.L., Clark, E.C., Muller, F.O. |
| Zdroj: |
Journal of Pharmaceutical Sciences; June 1975, Vol. 64 Issue: 6 p1041-1043, 3p |
| Abstrakt: |
A sensitive, specific, and quantitative GLC method for the determination of phendimetrazine in serum is described. The procedure involves the addition of an internal standard to serum samples, followed by extraction at pH 13 into toluene. The extracted bases are back‐extracted into 1 ml of 4 Mhydrochloric acid and again into 100 μl of chloroform after making the 4 Mhydrochloric acid extract basic with 1.5 ml of 4 Msodium hydroxide. The sensitivity of the method is such that 25 ng of material can be detected in 5 ml of serum. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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