Measurement of Hydrophile-Lipophile Balance of Surface-Active Agents

Autor: Chun, Alexander H.C., Martin, Alfred N.
Zdroj: Journal of Pharmaceutical Sciences; September 1961, Vol. 50 Issue: 9 p732-736, 5p
Abstrakt: An interfacial tension method was developed for the evaluation of hydrophile-lipophile balance (HLB) values of water-soluble surface-active agents. One-tenth per cent aqueous solutions of surfactant were overlayered with toluene and the interfacial tension measurements were made with a du Nouy tensiometer. A linear relationship resulted when the interfacial tension values were plotted against HLB values. This method does not apply to mixtures of surfactants and to natural emulsifiers. The HLB values are also related to H/L numbers.
Databáze: Supplemental Index