| Autor: |
Beamer, Robert L., Fickling, Carolyn S., Ewing, James H. |
| Zdroj: |
Journal of Pharmaceutical Sciences; August 1967, Vol. 56 Issue: 8 p1029-1032, 4p |
| Abstrakt: |
Studies have been conducted concerning the stereospecific nature of catalysts prepared by depositing palladium upon a poly-L-amino acid. The poly-L-amino acid chosen for this study was poly-L-leucine which was prepared from N-carboxy-L-leucine anhydride. The substrates employed in this work were α-methylcinnamic acid and α-acetamidocinnamic acid. Hydrogenation of α-methylcinnamic acid catalyzed by palladium-on-poly-L-leucine produced predominately R(−)-dihydro-α-methylcinnamic acid and hydrogenation of α-acetamidocinnamic acid using the same catalyst produced, after hydrolysis, S(−)-phenylalanine. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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