N-Chlorosaccharin as a Possible Chlorinating Reagent: Structure, Chlorine Potential, and Stability in Water and Organic Solvents

Autor: Dawn, Han-Son, Pitman, Ian H., Higuchi, Takeru, Young, Stephen
Zdroj: Journal of Pharmaceutical Sciences; July 1970, Vol. 59 Issue: 7 p955-959, 5p
Abstrakt: N-Chlorosaccharin is shown by its low chlorine potential (pKcp= 4.85 at 25°) to be a stronger chlorinating reagent in water than the commonly used chloramine-T or N-chlorosuccinimide. Its possible usefulness as a detoxifying or chlorinating reagent was further indicated by its solubility and stability in a variety of solvents. The mechanism of a reaction in which the imide bond of N-chlorosaccharin was cleaved in aqueous hypochlorite solution was also investigated.
Databáze: Supplemental Index