Radioimmunoassay of Minoxidil in Human Serum

Autor: Royer, Max E., Ko, Howard, Gilbertson, Terry J., McCall, John M., Johnston, Karen T., Stryd, Ronald
Zdroj: Journal of Pharmaceutical Sciences; September 1977, Vol. 66 Issue: 9 p1266-1269, 4p
Abstrakt: A simple, sensitive, and specific radioimmunoassay for determining minoxidil was developed. Antiserums to two minoxidil haptens were compared for cross-reactivity and assay levels on human serums. One antiserum had little cross-reactivity with minoxidil metabolites. The radioimmunoassay is specific for determining minoxidil directly in serum without extraction. Human serum minoxidil levels were determined from a single oral dose.
Databáze: Supplemental Index