Frozen Conformers of Clotrimazole: Reaction of Imidazole with 1-chloro-9-hydroxy-9-phenylxanthene
| Autor: | Warner, Paul L., Luber, Edward, Zusi, F.Christopher |
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| Zdroj: | Journal of Pharmaceutical Sciences; November 1979, Vol. 68 Issue: 11 p1453-1454, 2p |
| Abstrakt: | 1-Chloro-9-hydroxy-9-phenylxanthene reacts with imidazole at 180° to form a 5:1 mixture of the 9-(imidazo-1-yl)- and 9-(imidazo-2-yl)-1-chloro-9-phenylxanthenes. These products lack significant antifungal activity. |
| Databáze: | Supplemental Index |
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