Autor: |
Belal, Saied, Elsayedx, M.Abdel-Hady, Abdel-Hamid, Mohamed E., Abdine, Hassan |
Zdroj: |
Journal of Pharmaceutical Sciences; February 1981, Vol. 70 Issue: 2 p127-130, 4p |
Abstrakt: |
A simple and sensitive spectrophotometric method is described for the assay of naphazoline, clemizole, penicillin G sodium, and piperazine. The method was based on the formation of a charge transfer complex between these drugs as n-donors and chloranil, the π-acceptor. Conformity to Beer's law enabled the assay of dosage forms of these drugs. Compared with official methods, the results obtained were of equal accuracy. A more detailed investigation of the naphazoline—chloranil complex was made with respect to its composition, association constant, and free energy change. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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