| Autor: |
Perrault, Hélène, Coughlan, Mary, Marcotte, Jacques-Edouard, Drblik, Susan Pamela, Lamarre, André |
| Zdroj: |
Chest; January 1992, Vol. 101 Issue: 1 p42-51, 10p |
| Abstrakt: |
This study characterizes cardiac output response to progressive submaximal upright cycling in CF patients. Thirty-one CF patients as well as 11 aged-matched CF control subjects completed cardiac output determinations (CO2-rebreathing) at rest, and at submaximal exercise corresponding to 30, 50 and 75 percent V˙o2max, in both upright and supine positions. The V˙o2max was similar in three of four groups, but lower in those with severe CF. The cardiac output generally increased with exercise intensity in both positions, except in severe CF. The change from upright to supine posture resulted in a significant increase in SI at rest and for every submaximal exercise in control subjects, but not CF patients. These observations may suggest that the abnormal cardiac output response observed in severe CF could be related to a potential limitation in ventricular diastolic reserve found in all CF patients independent of disease severity which becomes more apparent under increased ventricular preload. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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