Substituted Spiro[isoxazolidine-3,2′-tricyclo[3.3.1.13,7]decane] Derivatives

Autor: Mullen, George B., Swift, Patricia A., Georgiev, Vassil St.
Zdroj: Journal of Pharmaceutical Sciences; December 1987, Vol. 76 Issue: 12 p930-934, 5p
Abstrakt: The preparation and potential anti-inflammatory activity of a series of novel substituted spiro[isoxazolidine-3,2′-tricyclo[3.3.1.13,7]decanes] (7, 11–30) are reported. The synthesis of the title compounds was accomplished via a 1,3-dipolar cycloaddition reaction of nitrones with appropriate olefins.
Databáze: Supplemental Index