Relationships Between Human Blood Groups, Bacterial Pathogens, and Urinary Tract Infections

Autor: Ratner, Joan J., Thomas, Virginia L., Forland, Marvin
Zdroj: The American Journal of the Medical Sciences; August 1986, Vol. 292 Issue: 2 p87-91, 5p
Abstrakt: Blood groups of 137 patients with acute pyelonephritis and chronic upper tract infection, cystitis, and asymptomatic bacteriuria were compared with those of a normal uninfected control population. In addition, the identified uropathogens were categorized according to the patient’s blood group. There was a significant association between the diagnosis of chronic upper tract infection and blood group B as compared with controls (p=<0.05, χ2). Analysis of the bacterial isolates showed that more patients with blood group B had infections with Pseudomonassp., Klebsiella pneumoniae, and Proteussp. than was expected; and fewer patients with blood group A had infections with Psuedomonasthan predicted (p=<0.05, χ2). There was an increased number of patients in blood group AB with infections caused by Escherichia coliand Klebsiella pneumoniae. These results suggest that an individual’s blood group may be a significant factor in the host-response to bacterial invasion and influence the development of infection with certain gram-negative bacilli.
Databáze: Supplemental Index