Application of High-Field NMR and Cryogenic Probe Technologies in the Structural Elucidation of Poecillastrin A, a New Antitumor Macrolide Lactam from the Sponge Poecillastra Species

Autor: Rashid, M. A., Gustafson, K. R., Crouch, R. C., Groweiss, A., Pannell, L. K., Van, Q. N., Boyd, M. R.
Zdroj: Organic Letters; September 2002, Vol. 4 Issue: 19 p3293-3296, 4p
Abstrakt: Poecillastrin A (1), a new polyketide-derived macrolide lactam, was isolated from a deep-water collection of the marine sponge Poecillastra species. The structure of poecillastrin A (1) was assigned using NMR data acquired at 500 MHz with an inverse-detection cryogenic probe and at 800 MHz with a room-temperature probe.
Databáze: Supplemental Index