Autor: |
Fomicheva, E., Nemirovich-Danchenko, E., Korneva, E. |
Zdroj: |
Bulletin of Experimental Biology and Medicine; June 2004, Vol. 137 Issue: 6 p544-547, 4p |
Abstrakt: |
We showed for the first time that prolactin stimulates the synthesis and release of immunomodulating cytokines and lymphocyte-activating factors (e.g., interleukin-1) by peritoneal macrophages. Prolactin abolished the stress-induced inhibition of proliferation of peripheral blood lymphocytes and increased cell sensitivity to regulatory effects of interleukin-1 in the reaction of lymphocyte blast transformation. These data illustrate the mechanism of immunoprotective activity of prolactin during stress. |
Databáze: |
Supplemental Index |
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