Autor: |
Kondratenko, R., Baltina, L., Vasil'eva, E., Baltina, L., Ismagilova, A., Nasyrov, Kh., Baschenko, N., Kireeva, R., Fridman, S., Tolstikov, G. |
Zdroj: |
Russian Journal of Bioorganic Chemistry; January 2004, Vol. 30 Issue: 1 p53-59, 7p |
Abstrakt: |
New cysteine-containing derivatives of glycyrrhizic acid were synthesized by its coupling with Cys(Bzl) esters or the Cys(Bzl)-Val-OButdipeptide by the active ester method (DCC/HOSu) or by Woodward's reagent K. The derivatives with Cys(Bzl) and Cys(Bzl)-Val residues attached to the carbohydrate part of the molecule stimulated the primary immune response and the reaction of delayed-Type hypersensitivity in mice at a dose of 2 mg/kg. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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