Abstrakt: |
Successful use of a diagnostic toxicology laboratory requires a complete understanding of the case in question. Different types of evidence must be integrated, including a thorough clinical and environmental history, observation of clinical signs, necropsy results, analytical chemistry findings, and occasionally, bioassay. The history and clinical/pathologic findings help identify the source of the toxicant, affected organ systems, and a list of rule-outs. If a systematic approach is accompanied by proper sample management, the practitioner optimizes the ability to handle complex poisoning cases in a successful and professionally rewarding fashion. The possibility of residues in food animal products must be considered in working up the toxicology case. |