| Autor: |
Campos, Juliana Coutinho, da Silva, Maria José Félix, dos Santos, Paulo Roberto Nascimento, Barros, Elaine Menezes, Pereira, Mayne de Oliveira, Seco, Bruna Mara Silva, Magagnin, Cibele Massotti, Leiroz, Leonardo Kalab, de Oliveira, Théo Gremen Mimary, Faria-Júnior, Célio de, Cerdeira, Louise Teixeira, Barth, Afonso Luís, Sampaio, Suely Carlos Ferreira, Zavascki, Alexandre Prehn, Poirel, Laurent, Sampaio, Jorge Luiz Mello |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; September 2015, Vol. 59 Issue: 12 p7387-7395, 9p |
| Abstrakt: |
ABSTRACTIn Enterobacteriaceae, the blaNDMgenes have been found in many different genetic contexts, and a wide diversity of plasmid scaffolds bearing those genes has been found. In August 2013, we identified NDM-1-producing Escherichia coliand Enterobacter hormaecheistrains from a single rectal swab sample from a patient hospitalized in Rio de Janeiro, Brazil, who had no history of travel abroad. Complete DNA sequencing using the Illumina platform and annotation of the two plasmids harboring the blaNDM-1gene, one from each strain, showed that they belonged to incompatibility groups IncFIIKand IncX3 and harbored a novel transposon named Tn3000. Similar genetic structures have been identified among other isolates in Brazil but also on plasmids from other continents. Our findings suggest that the blaNDM-1gene may be transmitted by Tn3000in different parts of the world. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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