Autor: |
Kim, Jin Hee, Lee, Sang Cheol, Lim, Jae Yong, Kim, Dong Seok, Yun, Hye Young, Kwon, Nyoun Soo, Im, Mie Jae, Baek, Kwang Jin |
Zdroj: |
Turk Biyokimya Dergisi = Turkish Journal of Biochemistry; October 2015, Vol. 40 Issue: 5 p376-385, 10p |
Abstrakt: |
Objective: Gαh (tissue transglutaminase; TGII), known as the α1B-adrenoceptor signal mediator, is a bifunctional enzyme possessing transglutaminase and guanosine triphosphatase activities. The microtubule-associated protein tau plays a role in formation of neurofibrillary tangles in Alzheimer’s disease (AD) brain. Tau is also known as a substrate of transglutaminase. We aimed to better understand the correlation between α1B-adrenoceptor signaling and AD. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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