| Abstrakt: |
Survival of children with hypothyroidism, congenital or acquired, until the childbearing age is not unusual. A successful pregnancy in such an individual, however, is unusual, if she has not received thyroid replacement therapy. We have been able to find in the literature reports of pregnancies occurring in 6 untreated cretins. In 1897, Townsend1presented a case of a typical cretin who became pregnant; no mention of therapy was made in this report. Five years later, Herrgott2reported a pregnancy in a juvenile hypothyroid patient; once again this article did not mention therapy. Burk and Kerr3referred to Merguet's cretinous patient who became pregnant without any thyroid hormone treatment. In 1943, in a review of the subject, Parkin and Greene4reported the coincidence of pregnancy and hypothyroidism in one juvenile hypothyroid patient and in one cretin. Finally, Zondek,5in the fourth edition of his “Diseases of the Endocrine Glands”, mentioned another untreated cretin who became pregnant. |
