| Autor: |
Pinto, Roberto Martín, Votta, Roberto A., Montuori, Esteban, Baleiron, Héctor |
| Zdroj: |
American Journal of Obstetrics and Gynecology; March 1964, Vol. 88 Issue: 6 p759-769, 11p |
| Abstrakt: |
1. Estradiol 17β in colloidal suspension in a dose of 100 mg. per 500 ml. of dextrose solution at 5 per cent is well tolerated both by the mother and the fetus when administered at a rate of 400 μg per minute.2. Estradiol 17β so administered increases uterine activity, showing a certain oxytocic action never described until the present time. This increase in the activity of the pregnant human uterus in vivo is reflected in the rise of the uterine tonus and in the intensity of contractions. These contractions are either painless or slightly painful.3. The action of estradiol 17β reduces the “threshold” of responsiveness to oxytocin of the pregnant uterus.4. Under the action of estradiol 17β there is an active ripening of the cervix. This is less apparent in cases of intrauterine dead fetus.5. The increase in the uterine activity caused by estradiol 17β does not mean that it should provoke, by itself, the onset of labor though this may happen in some cases. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
