| Abstrakt: |
Chronic opiate addiction has been associated with amenorrhea, anovulation, and infertility. Methadone, a synthetic narcotic, has been given daily to 95 addicted women who formerly used heroin. Twelve women were in the menopause or had had hysterectomy. Of the remaining 83 premenopausal women, all but one resumed regular menstruation. Thirteen pregnancies were seen, of which 8 were conceived on high levels of methadone, and in 5 methadone therapy was started after previous heroin addiction. All the pregnant women were maintained on methadone, and no effect of the drug on the pregnancies has been demonstrated. |
