| Autor: |
Szakács, György, Morovján, György, Tengerdy, Robert |
| Zdroj: |
Biotechnology Letters; April 1998, Vol. 20 Issue: 4 p411-415, 5p |
| Abstrakt: |
Of 68 Aspergillus terreus, three produced lovastatin with equivalent or better yield than strain ATCC 20542 originally described for lovastatin production. Medium optimization experiments with the best isolate (TUB F-514) indicated that lactose, rapeseed meal and KNO3 were the best carbon, organic nitrogen and inorganic nitrogen sources, respectively. In shake-flasks with optimized medium containing 4 % (w/v) lactose, 400 μg lovastatin/ml was produced, with a yield of 10 mg/g lactose. In solid substrate fermentation on extracted sweet sorghum pulp supplemented with cheese whey 1500 μg lovastatin/g dry weight was produced with a yield of 37.5 mg/g lactose. © Rapid Science Ltd. 1998 |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
Full text from SpringerLink