| Autor: |
Battelli, Maria Giulia, Barbieri, Luigi, Bolognesi, Andrea, Buonamici, Laura, Valbonesi, Paola, Polito, Letizia, Van Damme, Els J.M, Peumans, Willy J, Stirpe, Fiorenzo |
| Zdroj: |
FEBS Letters; January 1997, Vol. 408 Issue: 3 p355-359, 5p |
| Abstrakt: |
Lectins from Aegopodium podagraria(APA), Bryonia dioica(BDA), Galanthus nivalis(GNA), Irishybrid (IRA) and Sambucus nigra(SNAl), and a new lectin-related protein from Sambucus nigra(SNLRP) were studied to ascertain whether they had the properties of ribosome-inactivating proteins (RIP). IRA and SNLRP inhibited protein synthesis by a cell-free system and, at much higher concentrations, by cells and had polynucleotide:adenosine glycosidase activity, thus behaving like non-toxic type 2 (two chain) RIP. APA and SNAl had much less activity, and BDA and GNA did not inhibit protein synthesis. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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