Interleukin 10 reduces the severity of acute pancreatitis in rats

Autor: Rongione, AJ, Kusske, AM, Kwan, K, Ashley, SW, Reber, HA, McFadden, DW
Zdroj: Gastroenterology; March 1997, Vol. 112 Issue: 3 p960-967, 8p
Abstrakt: BACKGROUND & AIMS: Previous studies have documented the effectiveness of interleukin (IL)-10 if given before the onset of experimental acute pancreatitis. This study examined whether IL-10, a cytokine that inhibits macrophage release of inflammatory mediators, would alter the severity of acute pancreatitis if given before or after the induction of disease.
Databáze: Supplemental Index