| Autor: |
Piettre, A., Chevenier, E., Massardier, C., Gimbert, Y., Greene, A. E. |
| Zdroj: |
Organic Letters; September 2002, Vol. 4 Issue: 18 p3139-3142, 4p |
| Abstrakt: |
A potential route to the topoisomerase I inhibitor hypoxyxylerone is demonstrated by a highly convergent synthesis of the penta(O-methyl) derivative. The key step in the approach is an anionic homo-Fries rearrangement, little used to date in natural product synthesis and employed here for the first time with a dinaphthalenic substrate, to access the pentacyclic system of hypoxyxylerone. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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