Multitarget PCR Assay for Direct Detection of Penicillinase-Producing Neisseria gonorrhoeaefor Enhanced Surveillance of Gonococcal Antimicrobial Resistance

Autor: Buckley, Cameron, Trembizki, Ella, Baird, Robert W., Chen, Marcus, Donovan, Basil, Freeman, Kevin, Goire, Namraj, Guy, Rebecca, Lahra, Monica M., Regan, David, Whiley, David M.
Zdroj: Journal of Clinical Microbiology; May 2015, Vol. 53 Issue: 8 p2706-2708, 3p
Abstrakt: ABSTRACTA multitarget PCR was developed for the direct detection of penicillinase-producing Neisseria gonorrhoeae(PPNG). The assay was validated by testing 342 PPNG isolates and 415 clinical samples. The method is suitable for routine detection of PPNG strains. Its multitarget approach reduces the potential for false-negative results caused by sequence variations.
Databáze: Supplemental Index