| Autor: |
MacFarlane, Amanda J., Behan, Nathalie A., Field, Martha S., Williams, Andrew, Stover, Patrick J., Yauk, Carole L. |
| Zdroj: |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis; September 2015, Vol. 779 Issue: 1 p105-111, 7p |
| Abstrakt: |
•Folate is required for nucleotide synthesis and cellular methylation capacity.•Genotoxic consequences of folate insufficiency or excess remain unclear.•Folate deficiency in mice resulted in a higher frequency of RBC Pig-amutants.•Folate deficiency resulted in a higher micronucleus frequency in blood cells.•Folate protects somatic cells from mutagenesis and genome instability in mice. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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