| Autor: |
Hoebee, Barbara, Brouwer, Jaap, van de Putte, Pieter, Loman, Henk, Retel, Jan |
| Zdroj: |
Nucleic Acids Research; August 1988, Vol. 16 Issue: 16 p8147-8147, 1p |
| Abstrakt: |
Upon irradiation with gamma rays of an oxygenated aqueoua solution of double-stranded M13 DNA, a very specific mutation spectrum was found with respect to both the type and the positions in the DNA sequence. Of the 23 mutations, which were sequenced, 16 represent a C/G to G/C tranaversion. A C/G to T/A transition was found once and a G/C to T/A tranaversion twice. The remaining 4 mutations are frsmeshifts, 2 are identical and formed by the insertion of a G/C basepair; the other 2 mutations are due to a duplication of 10 basepaira situated at different positions but with a remarkable homology in base sequence. Fourteen mutationa, including the 2 duplications are found in the neighbourhood of a TGCT/ACGA sequence. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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